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Food and Drug Administration today warned patients and health care providers about the possible risk of atypical thigh bone (femoral) fracture in patients who take bisphosphonates, a class of drugs used to prevent and treat osteoporosis.

This reduces the amount of calcium that is released into the blood from bones and helps to lower your blood calcium level.

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During clinical trials, the most common side effects were nausea, diarrhea, headaches and skin irritation.

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BONJ therefore exists, but unfortunately reliable tests or markers for assessing the healing ability of the oral soft tissues and the underlying bone are not yet available.

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The International Osteoporosis Foundation (Chapurlat, 2015) states "when common pain killers are not effective, bisphosphonates can be proposed to reduce bone pain.

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